Incidence of amlodipine-induced gingival overgrowth in the rural population of Loni.

Autor:	Tejnani A; GSBS Medical Trust, Loni, Maharashtra, India., Mani A; Department of Periodontology, Rural Dental College, Loni, India., Sodhi NK; Private Practitioner, Loni, Maharashtra, India., Mehta A; Department of Periodontology, Hiranandani Hospital, Thane, Maharashtra, India., Gourkhede S; Department of Periodontology, Late Shri Yashwantrao Chavan Memorial Medical and Rural Development Foundation's Dental College, Maharashtra, India., Thorat V; Department of Periodontology, BVP Dental College, Navi Mumbai, Maharashtra, India., Marawar P; Department of Periodontology, Rural Dental College, Loni, India.
Jazyk:	angličtina
Zdroj:	Journal of Indian Society of Periodontology [J Indian Soc Periodontol] 2014 Mar; Vol. 18 (2), pp. 226-8.
DOI:	10.4103/0972-124X.131332
Abstrakt:	Aims: Since the incidence of gingival overgrowth induced by amlodipine remains poorly defined, this study was carried out with an aim to determine the incidence. Materials and Methods: Dental patients who received amlodipine (N = 115), for more than 3 months were studied to determine the drug-induced gingival overgrowth. Clinical diagnosis of drug-induced overgrowth was verified by disappearance or decreased severity of gingival overgrowth after withdrawal of the causative drug. Results: The prevalence rate of amlodipine-induced gingival hyperplasia among experimental patients was 3.4%, while it was not observed among the control subjects. Oral examination revealed gingival overgrowth as a lobular or nodular enlargement on interdental papilla located in the anterior interproximal regions. Conclusions: In this study, there was a significant relationship between gingival inflammation resulting from dental plaque and drug dosage, and hyperplasia.
Databáze:	MEDLINE
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