| Autor: |
Men K, Duan X, Wei XW, Gou ML, Huang MJ, Chen LJ, Qian ZY, Wei YQ; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, Chengdu 610041, People's Republic of China. goumaling@scu.edu.cn. |
| Jazyk: |
angličtina |
| Zdroj: |
Anti-cancer agents in medicinal chemistry [Anticancer Agents Med Chem] 2014; Vol. 14 (6), pp. 826-32. |
| DOI: |
10.2174/1871520614666140521122932 |
| Abstrakt: |
Quercetin, a natural protective bioflavonoid, possesses diverse pharmacologic effects, such as antioxidant, anti-inflammatory, anti-proliferative, and anti-angiogenic activities. Recently, quercetin's effect in cancer prevention and treatment was recognized. However, the poor water solubility and low-bioavailability of quercetin limit its clinical use in cancer therapy. Nanotechnology provides a method to create novel formulations for hydrophobic drug. Nanoparticles-delivered quercetin has attracted many attentions for its enhanced anticancer potential and promising clinical application. This review will discuss the application of nanotechnology in quercetin delivery for cancer therapy. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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