| Autor: |
Ayral F; WildTech, PERS,Université de Lyon-VetAgro Sup,Marcy l'Etoile,France., Artois J; Université de Rennes 2,Rennes Cedex,France., Zilber AL; WildTech, PERS,Université de Lyon-VetAgro Sup,Marcy l'Etoile,France., Widén F; The National Veterinary Institute (SVA),Department of Virology, Immunobiology and Parasitology, Uppsala,Sweden., Pounder KC; Institute of Integrative Biology,University of Liverpool,Liverpool,UK., Aubert D; Laboratory of Parasitology, EA 3800, SFR CAP-Santé FED 4231, National Reference Centre on Toxoplasmosis,University of Reims Champagne-Ardenne,Reims Cédex,France., Bicout DJ; Biomatématiques et Epidémiologie, EPSP-TIMC, UMR CNRS 5525, UFJ, VetAgro Sup, Marcy l'Etoile., Artois M; WildTech, PERS,Université de Lyon-VetAgro Sup,Marcy l'Etoile,France. |
| Abstrakt: |
Leptospira interrogans, hantaviruses (particularly Seoul virus), hepatitis E virus (HEV), and Toxoplasma gondii are rat-associated zoonoses that are responsible for human morbidity and mortality worldwide. This study aimed to describe the infection patterns of these four pathogens in wild rats (Rattus norvegicus) across socioeconomic levels in neighbourhoods in Lyon, France. The infection or exposure status was determined using polymerase chain reaction or serology for 178 wild rats captured in 23 locations; additionally, confirmatory culture or mouse inoculation was performed. Multivariate logistic regression analyses were used to investigate whether morphological and socioeconomic data could predict the infection status of the rats. This study revealed that the rat colony's age structure may influence the prevalence of L. interrogans, hantavirus, and HEV. In addition, areas with high human population densities and low incomes may be associated with a greater number of infected rats and an increased risk of disease transmission. |
