Glanzmann thrombasthenia associated with human immunodeficiency virus-positive patient.

Autor: Manne RK; Department of Oral Medicine and Radiology, Narayana Dental College and Hospital, Chintareddypalem, Nellore, Andhra Pradesh, India., Natarajan K; Department of Oral Medicine and Radiology, Narayana Dental College and Hospital, Chintareddypalem, Nellore, Andhra Pradesh, India., Patil R; Department of Oral Medicine and Radiology, Narayana Dental College and Hospital, Chintareddypalem, Nellore, Andhra Pradesh, India., Prathi VS; Department of Oral Medicine and Radiology, Narayana Dental College and Hospital, Chintareddypalem, Nellore, Andhra Pradesh, India., Beeraka SS; Department of Oral Medicine and Radiology, Narayana Dental College and Hospital, Chintareddypalem, Nellore, Andhra Pradesh, India., Kolaparthi VS; Department of Oral Medicine and Radiology, Narayana Dental College and Hospital, Chintareddypalem, Nellore, Andhra Pradesh, India.
Jazyk: angličtina
Zdroj: International journal of preventive medicine [Int J Prev Med] 2014 Apr; Vol. 5 (4), pp. 500-4.
Abstrakt: Glanzmann's thrombasthenia (GT) is an autosomal recessive inherited platelet function defect characterized by normal platelet count, prolonged bleeding time and abnormal clot retraction. This disease typically presents in infancy or early childhood and has proven to have very good prognosis. In this case study, a 22-year-old GT patient who also developed human immunodeficiency virus (HIV) infection after sometime is reported. The patient showed oral manifestations of gingival hyperplasia and petechial lesions. Unfortunately the detection of both thrombasthenia and HIV were done at considerably late stages which contributed to a poor prognosis. The patient died of cardiopulmonary arrest secondary to HIV, thrombasthenia and thrombocytopenia. The importance of early detection, supportive care and communication between the general and oral physician in management of the GT is also discussed.
Databáze: MEDLINE
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