Isolated non-hepatic metastasis from upper gastrointestinal adenocarcinoma: A case for surgical resection.

Autor:	Kiu AK; Department of Surgery, The Queen Elizabeth Hospital, 28 Woodville Road, Woodville South, SA 5011, Australia., Lord AN; Department of Surgery, The Queen Elizabeth Hospital, 28 Woodville Road, Woodville South, SA 5011, Australia., Trochsler MI; Department of Surgery, The Queen Elizabeth Hospital, 28 Woodville Road, Woodville South, SA 5011, Australia; Division of Surgery, University of Adelaide, Australia., Maddern GJ; Department of Surgery, The Queen Elizabeth Hospital, 28 Woodville Road, Woodville South, SA 5011, Australia; Division of Surgery, University of Adelaide, Australia., Kanhere HA; Department of Surgery, The Queen Elizabeth Hospital, 28 Woodville Road, Woodville South, SA 5011, Australia; Division of Surgery, University of Adelaide, Australia. Electronic address: kanhere.harsh@health.sa.gov.au.
Jazyk:	angličtina
Zdroj:	International journal of surgery case reports [Int J Surg Case Rep] 2014; Vol. 5 (6), pp. 307-10. Date of Electronic Publication: 2014 Apr 13.
DOI:	10.1016/j.ijscr.2014.04.004
Abstrakt:	Introduction: Upper Gastrointestinal Tract (UGIT) malignancy is an increasing problem in western society and its prognosis is generally poor. The prognosis dims even further with the presence of loco regional recurrences or distant metastasis. This article looks at the feasibility and potential benefit from resection of non-hepatic, non-nodal metastases and recurrences. Presentation of Case: Case 1. A 72-year-old male who underwent total gastrectomy for a gastric adenocarcinoma presented with a splenic mass 40 months later and underwent a splenectomy. He is disease free at 30 months post-metastectomy. Case 2. A 54-year-old male with oesophagogastric junctional adenocarcinoma, underwent an Ivor-Lewis oesophagectomy. He developed a distal pancreatic mass at 24 months follow-up and underwent distal pancreatectomy and splenectomy. He is disease free at 12 months post-metastectomy. Case 3. A 75-year-old male underwent subtotal gastrectomy for lesser curvature adenocarcinoma. At 42 months follow-up, he developed solitary abdominal wall recurrence. This was locally resected with clear margins. After 12 months, he developed another full thickness abdominal wall recurrence with involvement of the hepatic flexure. Enbloc resection including right hemicolectomy was performed and he is disease free at 3 months. Discussion: There is very scarce literature on resection of non-hepatic, non-nodal recurrences/distant metastasis in oesophagogastric cancers. Based on these cases, a surgical resection in selected cases may provide prolonged survival with good quality of life. Conclusion: Resection for isolated recurrences and metachronous metastasis from UGIT cancers may be worthwhile, especially if patients have minimal co-morbidities. (Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu