Hypocalcaemia following thyroidectomy unresponsive to oral therapy.

Autor: Etheridge ZC; Department of Diabetes and Endocrinology, Queen's Medical Centre, Nottingham University Hospitals NHS Trust, Nottingham, UK., Schofield C; Nottinghamshire Healthcare NHS Trust; Nottingham University Hospitals NHS Trust; Nottingham, UK., Prinsloo PJ; Department of Clinical Pathology, Nottingham University Hospitals NHS Trust; Nottingham, UK., Sturrock ND; Department of Diabetes and Endocrinology, Queen's Medical Centre, Nottingham University Hospitals NHS Trust, Nottingham, UK.
Jazyk: angličtina
Zdroj: Hormones (Athens, Greece) [Hormones (Athens)] 2014 Apr-Jun; Vol. 13 (2), pp. 286-9.
DOI: 10.1007/BF03401343
Abstrakt: Hypocalcaemia due to hypoparathyroidism following thyroidectomy is a relatively common occurrence. Standard treatment is with oral calcium and vitamin D replacement therapy; lack of response to oral therapy is rare. Herein we describe a case of hypoparathyroidism following thyroidectomy unresponsive to oral therapy in a patient with a complex medical history. We consider the potential causes in the context of calcium metabolism including: poor adherence, hungry bone syndrome, malabsorption, vitamin D resistance, bisphosphonate use and functional hypoparathyroidism secondary to magnesium deficiency. Malabsorption due to intestinal hurry was likely to be a contributory factor in this case and very large doses of oral therapy were required to avoid symptomatic hypocalcaemia.
Databáze: MEDLINE
Externí odkaz: