| Autor: |
Khaustova NA; BioClinicum Center, Moscow, Russia, khaunadia@gmail.com., Makeeva DS, Kondrashina OV, Fedotov NN, Nechaev IN, Savelov NA, Grinevich VN, Maltseva DV, Galatenko VV, Shkurnikov MY |
| Jazyk: |
angličtina |
| Zdroj: |
Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2014 Feb; Vol. 156 (4), pp. 486-90. Date of Electronic Publication: 2014 Mar 06. |
| DOI: |
10.1007/s10517-014-2381-8 |
| Abstrakt: |
We compared the results of real-time PCR analysis of gene expression in paired specimens breast cancer tissue fixed in RNAlater (Qiagen) stabilization reagent (FF samples) and in formalin (FFPE samples). A clear-cut linear relationship (correlation coefficient 0.76 ± 0.07) was detected between the gene expression logarithm values in FF and FFPE samples. This fact suggests that collections of paraffin blocks with formalin-fixed tissue specimens from patients with a many-year disease history can be effectively used in modern studies. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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