| Autor: |
Kuznetsov MR, Sergeeva NA, Koshkin VM, Boldin BV, Rodionov SV, Virganskiĭ AO, Kosykh IV, Lisenkov OP, Kuznetsova VF |
| Jazyk: |
ruština |
| Zdroj: |
Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery [Angiol Sosud Khir] 2014; Vol. 20 (1), pp. 8-14. |
| Abstrakt: |
Presented in the article are the results of studying antiaggregate activity of acetylsalicylic acid and clopidogrel in a total of 36 patients suffering from various-severity chronic arterial insufficiency of lower limbs on the background of atherosclerosis obliterans. The study was conducted prior to treatment for correct selection of a particular antiplatelet agent. The obtained results showed that clopidogrel was not always more efficient than acetylsalicylic acid, since there is individual sensitivity of each patients to a particular antiplatelet agent. Therefore, an individual approach is necessary to conservative therapy of arterial insufficiency of lower limbs. For some patients it is preferable to administer clopidogrel, for others - acetylsalicylic acid. In a series of cases combined treatment is justified, while some patients having low sensitivity to both acetylsalicylic acid and clopidogrel require careful selection of alternative agents influencing other thrombocyte receptors. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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