9-1-1: HSCs respond to emergency calls.
| Autor: | Welner RS; Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02151, USA., Kincade PW; Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA. Electronic address: kincade@omrf.org. |
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| Jazyk: | angličtina |
| Zdroj: | Cell stem cell [Cell Stem Cell] 2014 Apr 03; Vol. 14 (4), pp. 415-6. |
| DOI: | 10.1016/j.stem.2014.03.010 |
| Abstrakt: | In this issue of Cell Stem Cell, Zhao et al. (2014) and Schürch et al. (2014) describe two new stem cell mechanisms underlying protective responses to infection. In response to inflammatory signals, HSPCs and MSCs produce cytokines that stimulate HSC mobilization and differentiation toward innate immune cells at the expense of adaptive immune lineages. (Copyright © 2014 Elsevier Inc. All rights reserved.) |
| Databáze: | MEDLINE |
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