[Opsonic and anti-opsonic effects of the synovial fluid in patients with rheumatoid arthritis based on its effect on the complement-dependent adhesion of neutrophils].

Autor: Salikhov IG, Fomina LL, Maianskiĭ AN, Konyshkina TM
Jazyk: ruština
Zdroj: Laboratornoe delo [Lab Delo] 1989 (2), pp. 9-12.
Abstrakt: A method has been developed for the assessment of the synovial fluid (SF) complement-dependent opsonic characteristics basing on the intensity of neutrophil adhesion to SF-pretreated Sephadex granules. Examinations of 25 patients with rheumatoid arthritis have detected the lowest complement-dependent opsonization (CDD) in the patients with extraarticular symptoms. CDD showed a tendency to normalization over the course of intraarticular glucocorticoid therapy. No anti-opsonic effects of SF have been recorded. Examinations of 8 synovial exudates from patients with osteoarthrosis deformans have revealed SF CDD much higher than that in rheumatoid arthritis patients.
Databáze: MEDLINE