Cluster of Fusarium verticillioides bloodstream infections among immunocompetent patients in an internal medicine department after reconstruction works in Larissa, Central Greece.

Autor: Georgiadou SP; Department of Medicine and Research Laboratory of Internal Medicine, Medical School, University of Thessaly, Thessaly, Greece., Velegraki A; Mycology Research Laboratory, Department of Microbiology, Medical School, National and Kapodistrian University of Athens, Athens, Greece., Arabatzis M; Mycology Research Laboratory, Department of Microbiology, Medical School, National and Kapodistrian University of Athens, Athens, Greece., Neonakis I; Department of Microbiology, Medical School, University of Thessaly, Thessaly, Greece., Chatzipanagiotou S; Department of Biopathology and Clinical Microbiology, Athens Medical School, Aeginition Hospital, Athens, Greece., Dalekos GN; Department of Medicine and Research Laboratory of Internal Medicine, Medical School, University of Thessaly, Thessaly, Greece., Petinaki E; Department of Microbiology, Medical School, University of Thessaly, Thessaly, Greece. Electronic address: petinaki@med.uth.gr.
Jazyk: angličtina
Zdroj: The Journal of hospital infection [J Hosp Infect] 2014 Apr; Vol. 86 (4), pp. 267-71. Date of Electronic Publication: 2014 Feb 27.
DOI: 10.1016/j.jhin.2014.01.011
Abstrakt: Background: Fusarium spp. can cause disseminated infections, particularly in immunocompromised patients. Fusarium verticillioides is a human pathogen, and sporadic cases of fusariosis have been reported.
Aim: To report a nosocomial cluster of F. verticillioides bloodstream infections among seven immunocompetent inpatients following reconstruction works.
Methods: Identification was performed using macroscopic and microscopic morphology, and molecular assays (sequencing the nuclear ribosomal internal transcribed spacer region and translation elongation factor-1α gene). Susceptibility testing was performed in accordance with the guidelines of the Clinical and Laboratory Standards Institute. Environmental surveillance specimens were taken and cultured on Sabouraud dextrose agar plates.
Findings: In total, 16 blood cultures obtained from the seven patients were positive for F. verticillioides. All surveillance cultures were negative.
Conclusions: In order to prevent fungaemia, it is important to implement effective infection control measures, before, during and after demolition and construction activities in healthcare settings.
(Copyright © 2014 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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