| Autor: |
Brouwer PA; Laser Centre, Academic Medical Centre, Amsterdam, The Netherlands, NL., Van Der Meulen FW, Timmenga EJ, van Gemert MJ |
| Jazyk: |
angličtina |
| Zdroj: |
Lasers in medical science [Lasers Med Sci] 2000 Jan; Vol. 15 (1), pp. 31-4. |
| DOI: |
10.1007/s101030050044 |
| Abstrakt: |
A factor that might complicate the use of intraoperative photodynamic therapy (PDT) is a possible adverse effect on normal tissue recovery. In this study, rats with experimental skin incisions received intraoperative PDT (10 mg/kg haematoporphyrin derivative, 180 J/cm(2) laser light), immediately followed by closure. Healing was evaluated by tensile strength assessment of the incisions 21 days after PDT. No significant differences between the PDT-treated group and control groups were found. We therefore concluded that with respect to healing of skin incisions in rats, intraoperative PDT is not contraindicated. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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