| Autor: |
Skryma RN, Burdyga FV, Prevarskaia NB, Degtiar' VE, Kalashnikova LE |
| Jazyk: |
ruština |
| Zdroj: |
Neirofiziologiia = Neurophysiology [Neirofiziologiia] 1987; Vol. 19 (6), pp. 841-4. |
| Abstrakt: |
Lipoxygenase blocker BW755C has been studied for its effect on calcium inward current in intracellularly perfused voltage clamped and contraction of guinea-pig ureter smooth muscle. BW755C increased the Ca inward current in somatic membrane and inhibited contraction of the smooth muscle evoked by high-potassium solution. It is suggested that the effects observed are related to the changes in the level of cyclic nucleotides in cytoplasm due to the action of the final products of lypoxygenase breakdown of fatty acids from the cell membrane. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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