Pons herniation into skull base after cabergoline therapy of giant prolactinoma.

Autor: Moles Herbera J; Department of Neurosurgery, Miguel Servet University Hospital, 1-3 Isabel la Católica Av., 50009, Zaragoza, Spain, js_moles@hotmail.com., Rivero Celada D, Montejo Gañan I, Fustero de Miguel D, Fuentes Uliaque C, Vela Marín AC
Jazyk: angličtina
Zdroj: Pituitary [Pituitary] 2015 Feb; Vol. 18 (1), pp. 68-71.
DOI: 10.1007/s11102-014-0558-9
Abstrakt: Introduction: Pons herniation after cabergoline therapy for giant prolactinoma is a complication not documented in literature.
Case Report: We report a medium aged patient who developed secondary hemiparesis after 18 months of medical treatment. MRI revealed pons herniation into the clivus. There was improvement with conservative treatment. Secuencial MRIs are presented showing the tumor at the moment of the diagnosis, tumor shrinkage and pons herniation.
Discussion: Some studies have shown that a significant and rapid tumor shrinkage resulting from treatment with cabergoline can occur and it is thought that some complications are related with this tumor regression, as in the presented case.
Databáze: MEDLINE
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