| Autor: |
Dima-Cozma C; 1st Medical Department Rehabilitation Clinical Hospital lasi., Cojocaru DC; 1st Medical Department Rehabilitation Clinical Hospital lasi., Chiriac S; Cardiovascular Rehabilitation Clinic, University of Medicine and Pharmacy, Grigore T. Popa - Iasi., Negru R; 1st Medical Department Rehabilitation Clinical Hospital lasi., Mitu F; 1st Medical Department Rehabilitation Clinical Hospital lasi. |
| Jazyk: |
angličtina |
| Zdroj: |
Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi [Rev Med Chir Soc Med Nat Iasi] 2013 Jul-Sep; Vol. 117 (3), pp. 674-9. |
| Abstrakt: |
Ebstein's anomaly is a rare congenital heart disease, accounting for less than 1% of all congenital heart diseases, characterized by a wide clinical, electrocardiographic, echocardiographic, anatomic and prognostic polymorphism. The disease can be fatal since birth or may remain asymptomatic until adulthood, sometimes being associated with septal defects, transposition of great vessels, preexcitation syndromes, or left ventricular noncompaction. The genetic changes underlying this syndrome are not fully known, but in the cases associating left ventricular nonompaction a mutation in MYH7 gene encoding the beta-myosin heavy chain was recently detected. The authors present 2 cases of Ebstein's anomaly with different onset and course and discuss the current clinical, electrocardiographic and echocardiographic criteria used for prognostic stratification of Ebstein disease in relation to international literature. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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