Epinephrine, DNA integrity and oxidative stress in workers exposed to extremely low-frequency electromagnetic fields (ELF-EMFs) at 132 kV substations.

Autor: Tiwari R; UGC-Research Unit, Bhavan's New Science College , Hyderabad, Andhra Pradesh , India ., Lakshmi NK, Bhargava SC, Ahuja YR
Jazyk: angličtina
Zdroj: Electromagnetic biology and medicine [Electromagn Biol Med] 2015 Mar; Vol. 34 (1), pp. 56-62. Date of Electronic Publication: 2014 Jan 24.
DOI: 10.3109/15368378.2013.869755
Abstrakt: There is apprehension about widespread use of electrical and electromagnetic gadgets which are supposed to emit electromagnetic radiations. Reports are controversy. These electromagnetic fields (EMFs) have considerable effect on endocrine system of exposed subjects. This study was focused to assess the possible bioeffects of extremely low-frequency (ELF)-EMFs on epinephrine level, DNA damage and oxidative stress in subjects occupationally exposed to 132 kV high-voltage substations. The blood sample of 142 exposed subjects and 151 non-exposed individuals was analyzed. Plasma epinephrine was measured by enzyme-linked immunosorbent assay, DNA damage was studied by alkaline comet assay along with oxidative stress. Epinephrine levels of sub-groups showed mean concentration of 75.22  ±  1.46, 64.43  ±  8.26 and 48.47  ±  4.97 for high, medium and low exposed groups, respectively. DNA damage ranged between 1.69 µm and 9.91 µm. The oxidative stress levels showed significant increase. The individuals employed in the live-line procedures were found to be vulnerable for EM stress with altered epinephrine concentrations, DNA damage and increased oxidative stress.
Databáze: MEDLINE
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