| Autor: |
Zaitseva OO; Laboratory of Cryophysiology of Blood (T.V. Polezhaeva) of the Physiology Institute at the Komi Scientific Center, Ural Branch of the Russian Academy of Sciences, Komi Republic, Syktyvkar, Russian Federation. ddic@yandex.ru, Polezhaeva TV; Laboratory of Cryophysiology of Blood (T.V. Polezhaeva) of the Physiology Institute at the Komi Scientific Center, Ural Branch of the Russian Academy of Sciences, Komi Republic, Syktyvkar, Russian Federation., Khudyakov AN; Laboratory of Cryophysiology of Blood (T.V. Polezhaeva) of the Physiology Institute at the Komi Scientific Center, Ural Branch of the Russian Academy of Sciences, Komi Republic, Syktyvkar, Russian Federation., Solomina ON; Laboratory of Cryophysiology of Blood (T.V. Polezhaeva) of the Physiology Institute at the Komi Scientific Center, Ural Branch of the Russian Academy of Sciences, Komi Republic, Syktyvkar, Russian Federation., Laptev DS; Laboratory of Cryophysiology of Blood (T.V. Polezhaeva) of the Physiology Institute at the Komi Scientific Center, Ural Branch of the Russian Academy of Sciences, Komi Republic, Syktyvkar, Russian Federation., Svedentsov EP; Kirov Research Institute of Haematology and Blood Transfusion, Kirov, Russian Federation., Utemov SV; Kirov Research Institute of Haematology and Blood Transfusion, Kirov, Russian Federation., Kostyaev AA; Kirov Research Institute of Haematology and Blood Transfusion, Kirov, Russian Federation. |
| Abstrakt: |
NADPH oxidase activation was studied by detecting the reactive oxygen species (ROS) and the dynamics of neutrophil phagocytic activity in blood before freezing and one day after exposure to -20 degrees C in the presence of pectic polysaccharides. Pectins (excluding lemnan) were found to increase the phagocytic activity of neutrophils, promote the formation of ROS in these cells and enhance NADPH oxidase activity in the following order: bergenan, comaruman, lemnan, apiuman, and potamogetonan. Cryoprotective action of lemnan and comaruman was proposed to be related to their unique chemical structures. |
