The effects of finite population size and selection on the correlation between gene frequency changes at two different loci and on the amount of linkage disequilibrium.

Autor: Galley SJ; Department of Applied Statistics, University of Reading, Reading, Berkshire, England., Curnow RN
Jazyk: angličtina
Zdroj: TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik [Theor Appl Genet] 1972 Jan; Vol. 42 (8), pp. 335-45.
DOI: 10.1007/BF00275358
Abstrakt: A potentially infinite random-mating population of monoecious diploid individuals is subjected to a single cycle of sampling and selection based on the values of a quantitative character. In the absence of epistatic interactions, expressions are obtained for the correlation between the gene frequencies at two linked loci and for the mean and variance of linkage disequilibrium after one cycle of selection. Numerical results are presented for a range of population sizes and for various values of the genetic parameters.
Databáze: MEDLINE
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