Autologous chondrocyte implantation for cartilage injury treatment in Chiang Mai University Hospital: a case report.

Autor:	Wongtriratanachai P; Department of Orthopedics, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand., Pruksakorn D; Department of Orthopedics, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand., Pothacharoen P; Department of Biochemistry, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand., Nimkingratana P; Department of Orthopedics, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand., Pattamapaspong N; Department of Radiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand., Phornphutkul C; Department of Orthopedics, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand., Setsitthakun S; Blood Bank Unit, Chiang Mai University Hospital, Chiang Mai, Thailand., Fongsatitkul L; Blood Bank Unit, Chiang Mai University Hospital, Chiang Mai, Thailand., Phrompaet S; Department of Orthopedics, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Jazyk:	angličtina
Zdroj:	Journal of the Medical Association of Thailand = Chotmaihet thangphaet [J Med Assoc Thai] 2013 Nov; Vol. 96 (11), pp. 1518-22.
Abstrakt:	Autologous chondrocyte implantation (ACI) has become one of the standard procedures for articular cartilage defect treatment. This technique provides a promising result. However the procedural process requires an approach of several steps from multidisciplinary teams. Although the success of this procedure has been reported from Srinakharinvirot University since 2007, the application of ACI is still limited in Thailand due to the complexity of processes and stringent quality control. This report is to present the first case of the cartilage defect treatment using the first generation-ACI under Chiang Mai University's (CMU) own facility and Ethics Committee. This paper also reviews the process of biotechnology procedures, patient selection, surgical, and rehabilitation techniques. The success of the first case is an important milestone for the further development of the CMU Human Translational Research Laboratory in near future.
Databáze:	MEDLINE
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