Limb salvage surgery in bone tumors: a retrospective study of 50 cases in a single center.

Autor: Chauhan A; Department of Surgical Oncology, Command Hospital(CC), Lucknow, India., Joshi GR; Department of Orthopaedic, Command Hospital(SC), Pune, India., Chopra BK; Joint replacement Center, AHRR, Delhi, India., Ganguly M; Department of Surgical Oncology, Command Hospital(CC), Lucknow, India., Reddy GR; Joint replacement Center, AHRR, Delhi, India.
Jazyk: angličtina
Zdroj: Indian journal of surgical oncology [Indian J Surg Oncol] 2013 Sep; Vol. 4 (3), pp. 248-54. Date of Electronic Publication: 2013 Mar 20.
DOI: 10.1007/s13193-013-0229-8
Abstrakt: Modular segmental replacement system (MSRS) is one of the options for Limb conservation surgery in bone tumors. The study analyses a single center experience of use of MSRS for limb conservation in cases of primary bone tumors. Retrospective analysis was done for a series of cases of limb salvage procedures done over a five year period. All Patients with bone tumors who underwent limb salvage procedures utilising MSRS prosthesis were included in the study. The patients' record were perused for pre operative staging; neoadjuvant therapy used, if any; surgical procedure done; follow-up for prosthesis related complications and overall survival achieved. Total of 50 cases studied,included 28 males and 22 females . Median age at diagnosis of 28 (10-73) years. Tumor localized in lower limb in 38 patients, and upper limb in 12 patients. Tumors were malignant in 28 patients (56 %) and benign in 22 (44 %). The most common diagnosis was osteosarcoma (21 patients (42 %)) . The median resection length was 15 cm (range 6-25). High grade tumors (grade 2a and 2b) was found in 27 of 29 cases(93.1 %) . 14 patients had prosthesis related complications. The mean follow-up was 5 years (range: 3-7). 42 patients of 50 were alive with the endoprosthesis at the last follow-up. Survival rate of prosthesis is 84 %. The modular segmental-replacement system prosthesis favoured by us in limb sparing surgery for bone tumors results in satisfactory results in terms of tumor control and limb function.
Databáze: MEDLINE
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