Toxicity studies of analogs of 2-tridecanone, a naturally occurring toxicant from a wild tomato.

Autor: Dimock MB; Department of Entomology, North Carolina State University, 27650, Raleigh, North Carolina., Kennedy GG, Williams WG
Jazyk: angličtina
Zdroj: Journal of chemical ecology [J Chem Ecol] 1982 May; Vol. 8 (5), pp. 837-42.
DOI: 10.1007/BF00994783
Abstrakt: Toxicity bioassays of the naturally occurring insecticide 2-tridecanone and a group of structural analogs against the tomato fruitworm (Heliothis zea) reveal a significant influence of chain length on toxicity of methyl ketones. This effect may be due to the differential ability of these compounds to penetrate lipid barriers and reach the active site, since a close relationship is seen between toxicity and lipophilicity. Congeners of chain lenths 15 and over are less active than predicted by this relationship, possibly due to steric effects.
Databáze: MEDLINE