| Autor: |
Ramgren SD; Department of Chemistry and Biochemistry University of California , Los Angeles, California 90095-1569, United States., Garg NK |
| Jazyk: |
angličtina |
| Zdroj: |
Organic letters [Org Lett] 2014 Feb 07; Vol. 16 (3), pp. 824-7. Date of Electronic Publication: 2014 Jan 09. |
| DOI: |
10.1021/ol403570z |
| Abstrakt: |
A simple method for the preparation of aryl methyl ketones is reported. The transformation involves the Pd-catalyzed coupling of an acyl anion equivalent, acetyltrimethylsilane, with aryl bromides to afford the corresponding acetylated arenes in synthetically useful yields. The methodology is tolerant of heterocycles and provides a new method for arene functionalization. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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