Delay discounting and task performance consistency in patients with schizophrenia.

Autor: Weller RE; Department of Psychology, The University of Alabama at Birmingham, Birmingham, AL 35294-1170, United States., Avsar KB; Department of Psychology, The University of Alabama at Birmingham, Birmingham, AL 35294-1170, United States; Department of Psychiatry and Behavioral Neurobiology, The University of Alabama at Birmingham, Birmingham, AL 35294-0017, United States., Cox JE; Department of Psychology, The University of Alabama at Birmingham, Birmingham, AL 35294-1170, United States., Reid MA; Department of Psychiatry and Behavioral Neurobiology, The University of Alabama at Birmingham, Birmingham, AL 35294-0017, United States; Department of Biomedical Engineering, The University of Alabama at Birmingham, Birmingham, AL 35294-2182, United States., White DM; Department of Psychiatry and Behavioral Neurobiology, The University of Alabama at Birmingham, Birmingham, AL 35294-0017, United States., Lahti AC; Department of Psychiatry and Behavioral Neurobiology, The University of Alabama at Birmingham, Birmingham, AL 35294-0017, United States. Electronic address: alahti@uab.edu.
Jazyk: angličtina
Zdroj: Psychiatry research [Psychiatry Res] 2014 Feb 28; Vol. 215 (2), pp. 286-93. Date of Electronic Publication: 2013 Dec 04.
DOI: 10.1016/j.psychres.2013.11.013
Abstrakt: To study impaired goal-oriented behavior in schizophrenia (SZ), we used a delay discounting task, which consists of a series of choices between receiving a small immediate or larger delayed reward. Few studies of delay discounting have evaluated response consistency (R(2)), which is especially relevant in SZ because of documented inconsistency in task performance. We calculated the rate of discounting (k) and R(2) in SZ (n=35) and healthy controls (HC; n=21). Using a criterion value of R(2)>0.60 to define consistent performance allowed us to compare discounting in consistent SZ and HC, as well as in inconsistent SZ. Groups did not differ significantly in smoking. Compared to HC, consistent SZ showed greater delay discounting. Both groups exhibited similar patterns of decreasing immediate choices across trial categories, although the decrease was less for SZ. Separate analyses on smokers and non-smokers showed that this group difference was carried by the non-smokers. Inconsistent SZ discounted more than HC and consistent SZ, but their aberrant pattern of choices casts doubt on the validity of their calculated k values.
(© 2013 Published by Elsevier Ireland Ltd.)
Databáze: MEDLINE
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