Air kerma strength characterization of a GZP6 Cobalt-60 brachytherapy source.

Autor: Toossi MT; Medical Physics Department, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran., Ghorbani M; Medical Physics Department, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran., Mowlavi AA; Physics Department, School of Sciences, Sabzevar Tarbiat Moallem University, Sabzevar, Iran., Taheri M; Reza Radiotherapy and Oncology Center, Mashhad, Iran., Layegh M; Department of Radiotherapy, Omid University Hospital, Mashhad, Iran., Makhdoumi Y; Reza Radiotherapy and Oncology Center, Mashhad, Iran., Meigooni AS; Comprehensive Cancer Center of Nevada, 3730 S. Eastern Avenue, Las Vegas, NV, United States.
Jazyk: angličtina
Zdroj: Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology [Rep Pract Oncol Radiother] 2010 Nov 09; Vol. 15 (6), pp. 190-4. Date of Electronic Publication: 2010 Nov 09 (Print Publication: 2010).
DOI: 10.1016/j.rpor.2010.10.002
Abstrakt: Background: Task group number 40 (TG-40) of the American Association of Physicists in Medicine (AAPM) has recommended calibration of any brachytherapy source before its clinical use. GZP6 afterloading brachytherapy unit is a (60)Co high dose rate (HDR) system recently being used in some of the Iranian radiotherapy centers.
Aim: In this study air kerma strength (AKS) of (60)Co source number three of this unit was estimated by Monte Carlo simulation and in air measurements.
Materials and Methods: Simulation was performed by employing the MCNP-4C Monte Carlo code. Self-absorption of the source core and its capsule were taken into account when calculating air kerma strength. In-air measurements were performed according to the multiple distance method; where a specially designed jig and a 0.6 cm(3) Farmer type ionization chamber were used for the measurements. Monte Carlo simulation, in air measurement and GZP6 treatment planning results were compared for primary air kerma strength (as for November 8th 2005).
Results: Monte Carlo calculated and in air measured air kerma strength were respectively equal to 17240.01 μGym(2) h(-1) and 16991.83 μGym(2) h(-1). The value provided by the GZP6 treatment planning system (TPS) was "15355 μGym(2) h(-1)".
Conclusion: The calculated and measured AKS values are in good agreement. Calculated-TPS and measured-TPS AKS values are also in agreement within the uncertainties related to our calculation, measurements and those certified by the GZP6 manufacturer. Considering the uncertainties, the TPS value for AKS is validated by our calculations and measurements, however, it is incorporated with a large uncertainty.
Databáze: MEDLINE