Prevalence of antibiotic resistance in US hospitals.

Autor: Edelsberg J; Policy Analysis Inc. (PAI), Brookline, MA, USA., Weycker D; Policy Analysis Inc. (PAI), Brookline, MA, USA. Electronic address: dweycker@pai2.com., Barron R; Amgen Inc., Thousand Oaks, CA, USA., Li X; Amgen Inc., Thousand Oaks, CA, USA., Wu H; Policy Analysis Inc. (PAI), Brookline, MA, USA; Wentworth Institute of Technology, Department of Computer Science and Networking, Boston, MA, USA., Oster G; Policy Analysis Inc. (PAI), Brookline, MA, USA., Badre S; Amgen Inc., Thousand Oaks, CA, USA., Langeberg WJ; Amgen Inc., Thousand Oaks, CA, USA., Weber DJ; University of North Carolina at Chapel Hill, Schools of Medicine and Public Health, Chapel Hill, NC, USA.
Jazyk: angličtina
Zdroj: Diagnostic microbiology and infectious disease [Diagn Microbiol Infect Dis] 2014 Mar; Vol. 78 (3), pp. 255-62. Date of Electronic Publication: 2013 Nov 15.
DOI: 10.1016/j.diagmicrobio.2013.11.011
Abstrakt: The percentage of isolates resistant to essential antibiotics among clinically significant bacterial pathogens was evaluated using data from 80089 qualifying admissions in 19 US hospitals (2007-2010). Percentage resistant was highest for the following pathogen/antibiotic pairs: Enterococcus faecium/vancomycin (87.1% [95% CI 86.0-88.1] of 4024 isolates), Staphylococcus aureus/oxacillin-methicillin (56.8% [56.1-57.4] of 23477 isolates), S. aureus/clindamycin (39.7% [39.1-40.4] of 21133 isolates), Pseudomonas aeruginosa/fluoroquinolones (32.6% [31.8-33.5] of 10982 isolates), and Escherichia coli/fluoroquinolones (31.3% [30.8-31.8] of 30715 isolates). The percentage resistant was 3.9% (3.2-4.9) for E. faecium/daptomycin (n = 2029 isolates). While these results are consistent with those from earlier studies in many respects, the percentage of E. faecium isolates resistant to daptomycin, while still small, is higher than has been reported to date.
(Copyright © 2014 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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