Computed tomography demonstrates abnormalities of contralateral ear in subjects with unilateral sensorineural hearing loss.

Autor: Marcus S; New York University Langone Medical Center, Department of Otolaryngology, 550 First Avenue, NBB 5E5, New York, NY 10016, United States., Whitlow CT; Department of Radiology, Wake Forest™ School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157, United States., Koonce J; Mountain Empire Radiology, 1301 Sunset Drive Suite 3, Johnson City, TN 37604, United States., Zapadka ME; Department of Radiology, Wake Forest™ School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157, United States., Chen MY; Department of Radiology, Wake Forest™ School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157, United States., Williams DW 3rd; Head & Neck Radiology, Neuroradiology, Department of Radiology, Wake Forest™ School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157, United States., Lewis M; Department of Otolaryngology, Wake Forest™ School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157, United States., Evans AK; Department of Otolaryngology, Wake Forest™ School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157, United States. Electronic address: akevans@wakehealth.edu.
Jazyk: angličtina
Zdroj: International journal of pediatric otorhinolaryngology [Int J Pediatr Otorhinolaryngol] 2014 Feb; Vol. 78 (2), pp. 268-71. Date of Electronic Publication: 2013 Nov 25.
DOI: 10.1016/j.ijporl.2013.11.020
Abstrakt: Purpose: Prior studies have associated gross inner ear abnormalities with pediatric sensorineural hearing loss (SNHL) using computed tomography (CT). No studies to date have specifically investigated morphologic inner ear abnormalities involving the contralateral unaffected ear in patients with unilateral SNHL. The purpose of this study is to evaluate contralateral inner ear structures of subjects with unilateral SNHL but no grossly abnormal findings on CT.
Materials and Methods: IRB-approved retrospective analysis of pediatric temporal bone CT scans. 97 temporal bone CT scans, previously interpreted as "normal" based upon previously accepted guidelines by board certified neuroradiologists, were assessed using 12 measurements of the semicircular canals, cochlea and vestibule. The control-group consisted of 72 "normal" temporal bone CTs with underlying SNHL in the subject excluded. The study-group consisted of 25 normal-hearing contralateral temporal bones in subjects with unilateral SNHL. Multivariate analysis of covariance (MANCOVA) was then conducted to evaluate for differences between the study and control group.
Results: Cochlea basal turn lumen width was significantly greater in magnitude and central lucency of the lateral semicircular canal bony island was significantly lower in density for audiometrically normal ears of subjects with unilateral SNHL compared to controls.
Conclusion: Abnormalities of the inner ear were present in the contralateral audiometrically normal ears of subjects with unilateral SNHL. These data suggest that patients with unilateral SNHL may have a more pervasive disease process that results in abnormalities of both ears. The findings of a cochlea basal turn lumen width disparity >5% from "normal" and/or a lateral semicircular canal bony island central lucency disparity of >5% from "normal" may indicate inherent risk to the contralateral unaffected ear in pediatric patients with unilateral sensorineural hearing loss.
(Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.)
Databáze: MEDLINE
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