| Autor: |
Silva LG; Universidade do Oeste Paulista, Presidente Prudente Regional Hospital, Dermatology Service, Presidente PrudenteSP, Brazil., Sasso LS; Universidade do Oeste Paulista, Presidente Prudente Regional Hospital, Ophthalmology Service, Presidente PrudenteSP, Brazil., Nelli CJ; Universidade do Oeste Paulista, Presidente Prudente Regional Hospital, Dermatology Service, Presidente PrudenteSP, Brazil., Bernardes Filho F; Rio de Janeiro Santa Casa da MisericórdiaProfessor Rubem David Azulay Institute of DermatologyHospital, Rio de JaneiroRJ, Brazil., Abreu MA; Dermatology Service, Presidente Prudente Regional Hospital, Universidade do Oeste Paulista, Rio de JaneiroRJ, Brazil. |
| Abstrakt: |
The change in immunological response obtained by immunobiologics has brought a new paradigm to the treatment of immune-mediated disorders. As a result of their efficacy, there is a positive impact on the quality of life of patients. However, severe side effects, such as demyelination of cerebral or peripheral nerves, have been reported. After review of literature using PubMed and MEDLINE data from 2000 to 2012, we identified the cases correlating the biological uniterms and optic neuritis. This article reports the first Brazilian optic neuritis case associated with the use of immunobiologics. This publication is justified by the rarity of the disease and atypical therapeutical evolution. |
