| Autor: |
Lavorato FG; Rio de Janeiro State University, Pedro Ernesto University Hospital, Rio de JaneiroRJ, Brazil., Alves Mde F; Rio de Janeiro State University, Pedro Ernesto University Hospital, Rio de JaneiroRJ, Brazil., Maceira JM; Rio de Janeiro Federal University, Rio de JaneiroRJ, Brazil., Unterstell N; Rio de Janeiro State University, Pedro Ernesto University Hospital, Rio de JaneiroRJ, Brazil., Serpa LA; Rio de Janeiro State University, Pedro Ernesto University Hospital, Rio de JaneiroRJ, Brazil., Azulay-Abulafia L; Rio de Janeiro State University. |
| Jazyk: |
angličtina |
| Zdroj: |
Anais brasileiros de dermatologia [An Bras Dermatol] 2013 Nov-Dec; Vol. 88 (6 Suppl 1), pp. 32-5. |
| DOI: |
10.1590/abd1806-4841.20132531 |
| Abstrakt: |
A 57-year-old woman presented with periorbital ecchymoses, laxity in skin folds, polyneuropathy and bilateral carpal tunnel syndrome. A skin biopsy of the axillary lesion demonstrated fragmentation of elastic fibers, but with a negative von Kossa stain, consistent with cutis laxa. The diagnosis of primary systemic amyloidosis was made by the presence of amyloid material in the eyelid using histopathological techniques, besides this, the patient was also diagnosed with purpura, polyneuropathy, bilateral carpal tunnel syndrome and monoclonal gammopathy. She was diagnosed as suffering from multiple myeloma based on the finding of 40% plasma cells in the bone marrow, component M in the urine and anemia. The patient developed blisters with a clear content, confirmed as mucinosis by the histopathological exam. The final diagnoses were: primary systemic amyloidosis, acquired cutis laxa and mucinosis, all related to multiple myeloma. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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