Does hyperglycemia in pregnancy change fetal kidney growth? A longitudinal prospective study.
| Autor: | Neves HM, Sgarbosa F, Calderon IM, Vianna LS, Santini AC, Sieiro Netto L, Dias A |
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| Jazyk: | angličtina |
| Zdroj: | Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia [Rev Bras Ginecol Obstet] 2013 Oct; Vol. 35 (10), pp. 442-6. |
| DOI: | 10.1590/s0100-72032013001000003 |
| Abstrakt: | Purpose: To measure fetal renal volume in normoglycemic and hyperglycemic pregnancies. Methods: A longitudinal prospective study was conducted and included 92 hyperglycemic and 339 normoglycemic pregnant women attended at the prenatal service of a hospital from Rio de Janeiro State. Ultrasound examinations were performed to estimate gestational age at baseline and the kidney volume was estimated using the prolate ellipsoid volume equation. Results: Fetal kidney volume growth between normoglycemic and hyperglycemic pregnancies are significantly different. The fetal kidney volume growth in pregnancy is positively correlated with gestational age explained by these predictor equations, by group: normal renal volume = exp (6.186 + 0.09 × gestational week); hyperglycemic renal volume = exp (6.978 + 0.071 × gestational week) and an excessive growth pattern for hyperglycemic pregnancies may be established according to gestational age. Conclusion: This is important for early detection of abnormalities in pregnancy, particularly in diabetic mothers. |
| Databáze: | MEDLINE |
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