| Autor: |
Asrican B; Department of Neurobiology, Duke University Medical Center Durham, NC, USA., Augustine GJ, Berglund K, Chen S, Chow N, Deisseroth K, Feng G, Gloss B, Hira R, Hoffmann C, Kasai H, Katarya M, Kim J, Kudolo J, Lee LM, Lo SQ, Mancuso J, Matsuzaki M, Nakajima R, Qiu L, Tan G, Tang Y, Ting JT, Tsuda S, Wen L, Zhang X, Zhao S |
| Jazyk: |
angličtina |
| Zdroj: |
Frontiers in neural circuits [Front Neural Circuits] 2013 Nov 26; Vol. 7, pp. 160. Date of Electronic Publication: 2013 Nov 26 (Print Publication: 2013). |
| DOI: |
10.3389/fncir.2013.00160 |
| Abstrakt: |
Here we characterize several new lines of transgenic mice useful for optogenetic analysis of brain circuit function. These mice express optogenetic probes, such as enhanced halorhodopsin or several different versions of channelrhodopsins, behind various neuron-specific promoters. These mice permit photoinhibition or photostimulation both in vitro and in vivo. Our results also reveal the important influence of fluorescent tags on optogenetic probe expression and function in transgenic mice. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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