| Autor: |
Viana Freitas BR; Disciplina de Gastroenterologia, Departamento de Clínica Médica, Universidade Estadual de Campinas, Rua Tessália Vieira de Camargo 126, Campinas 13083-887, Brazil., Kibune Nagasako C, Pavan CR, Silva Lorena SL, Guerrazzi F, Saddy Rodrigues Coy C, Ayrizono Mde L, Mesquita MA |
| Jazyk: |
angličtina |
| Zdroj: |
Gastroenterology research and practice [Gastroenterol Res Pract] 2013; Vol. 2013, pp. 384561. Date of Electronic Publication: 2013 Nov 11. |
| DOI: |
10.1155/2013/384561 |
| Abstrakt: |
Background. Fecal immunochemical tests (FITs) have been used for colorectal cancer (CRC) screening in several countries. There is lack of information concerning diagnostic performances of this method in Brazil. Methods. Patients scheduled for elective colonoscopy provided one stool sample one week before colonoscopy. The accuracy of a qualitative FIT for detection of CRC and advanced adenomas was determined. Results. Overall 302 patients completed the study. Among them, 53.5% were high risk patients referred for screening or surveillance. Nine (3%) CRCs and 11 (3.6%) advanced adenomas were detected by colonoscopy. Sensitivity and specificity for CRC were, respectively, 88.9% and 87.6%. For advanced adenomas, sensitivity was 63.6% and specificity 87.6%. Conclusion. Our results showed good sensitivity and specificity of the FIT for detecting advanced neoplasias. This method may be a valuable tool for future screening programs in Brazil. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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