| Autor: |
Madsen RD, Saeed FA, Gray O, Fendly BM, Coates SR |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of clinical microbiology [J Clin Microbiol] 1986 Oct; Vol. 24 (4), pp. 680-3. |
| DOI: |
10.1128/jcm.24.4.680-683.1986 |
| Abstrakt: |
A murine immunoglobulin G1 monoclonal antibody was produced that binds to a protease-sensitive, periodate-insensitive epitope on a 43,000-molecular-weight Mycoplasma pneumoniae membrane polypeptide. The 43,000-molecular-weight polypeptide appeared to be a major antigenic component of M. pneumoniae, as determined by immunoblot analysis. This monoclonal antibody reacted with 33 different clinical isolates of M. pneumoniae, but not with normal-flora Mycoplasma species or 18 other microorganisms potentially inhabiting the normal or diseased human respiratory tract. This apparent species-specific monoclonal antibody may have application for the detection of M. pneumoniae antigen in clinical specimens. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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