Digitally enhanced thin layer chromatography: further development and some applications in isotopic chemistry.
| Autor: | Manthorpe DP; Department of Chemistry, Faculty of Engineering and Physical Sciences, University of Surrey, Guildford, GU2 7XH, UK., Lockley WJ |
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| Jazyk: | angličtina |
| Zdroj: | Journal of labelled compounds & radiopharmaceuticals [J Labelled Comp Radiopharm] 2013 Sep; Vol. 56 (11), pp. 544-52. Date of Electronic Publication: 2013 Jul 23. |
| DOI: | 10.1002/jlcr.3052 |
| Abstrakt: | Improvements to thin layer chromatography (TLC) analysis can be made easily and cheaply by the application of digital colour photography and image analysis. The combined technique, digitally enhanced TLC (DE-TLC), is applicable to the accurate quantification of analytes in mixtures, to reaction monitoring and to other typical uses of TLC. Examples are given of the application of digitally enhanced TLC to: the deuteromethylations of theophylline to [methyl-(2)H3]caffeine and of umbelliferone to [(2)H3]7-methoxycoumarin; the selection of tertiary amine bases in deuterodechlorination reactions; stoichiometry optimisation in the borodeuteride reduction of quinizarin (1,4-dihydroxyanthraquinone) and to the assessment of xanthophyll yields in Lepidium sativum seedlings grown in deuterated media. (Copyright © 2013 John Wiley & Sons, Ltd.) |
| Databáze: | MEDLINE |
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