Enantioselective propargylation and allenylation reactions of ketones and imines.

Autor: Wisniewska HM; Department of Chemistry, University of California , Irvine, California 92697-2025, United States., Jarvo ER
Jazyk: angličtina
Zdroj: The Journal of organic chemistry [J Org Chem] 2013 Dec 06; Vol. 78 (23), pp. 11629-36. Date of Electronic Publication: 2013 Nov 23.
DOI: 10.1021/jo4019107
Abstrakt: Enantioselective propargylation and allenylation reactions pose an interesting challenge because they require control of regioselectivity as well as enantioselectivity. This review presents recent advances in enantioselective propargylation and allenylation reactions of ketones and imines. In this context, a brief discussion of the possible mechanisms of these transformations and consequences for regioselectivity is provided.
Databáze: MEDLINE