| Autor: |
Wiser MJ; BEACON Center for the Study of Evolution in Action, Michigan State University, East Lansing, MI 48824, USA., Ribeck N, Lenski RE |
| Jazyk: |
angličtina |
| Zdroj: |
Science (New York, N.Y.) [Science] 2013 Dec 13; Vol. 342 (6164), pp. 1364-7. Date of Electronic Publication: 2013 Nov 14. |
| DOI: |
10.1126/science.1243357 |
| Abstrakt: |
Experimental studies of evolution have increased greatly in number in recent years, stimulated by the growing power of genomic tools. However, organismal fitness remains the ultimate metric for interpreting these experiments, and the dynamics of fitness remain poorly understood over long time scales. Here, we examine fitness trajectories for 12 Escherichia coli populations during 50,000 generations. Mean fitness appears to increase without bound, consistent with a power law. We also derive this power-law relation theoretically by incorporating clonal interference and diminishing-returns epistasis into a dynamical model of changes in mean fitness over time. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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