| Autor: |
Nery MW; Postgraduate Studies Program, Institute of Tropical Pathology and Public Health, Federal University of Goiás, Brazil ; Department of Medicine, Catholic University of Goiás, Brazil., Martelli CM, Silveira EA, de Sousa CA, Falco Mde O, de Castro Ade C, Esper JT, Souza LC, Turchi MD |
| Jazyk: |
angličtina |
| Zdroj: |
TheScientificWorldJournal [ScientificWorldJournal] 2013 Oct 21; Vol. 2013, pp. 969281. Date of Electronic Publication: 2013 Oct 21 (Print Publication: 2013). |
| DOI: |
10.1155/2013/969281 |
| Abstrakt: |
This study aims to estimate the risk of cardiovascular disease (CVD) and to assess the agreement between the Framingham, Framingham with aggravating factors, PROCAM, and DAD equations in HIV-infected patients. A cross-sectional study was conducted in an outpatient centre in Brazil. 294 patients older than 19 years were enrolled. Estimates of 10-year cardiovascular risk were calculated. The agreement between the CVD risk equations was assessed using Cohen's kappa coefficient. The participants' mean age was 36.8 years (SD = 10.3), 76.9% were men, and 66.3% were on antiretroviral therapy. 47.8% of the participants had abdominal obesity, 23.1% were current smokers, 20.0% had hypertension, and 2.0% had diabetes. At least one lipid abnormality was detected in 72.8%, and a low HDL-C level was the most common. The majority were classified as having low risk for CV events. The percentage of patients at high risk ranged from 0.4 to 5.7. The PROCAM score placed the lowest proportion of the patients into a high-risk group, and the Framingham equation with aggravating factors placed the highest proportion of patients into the high-risk group. Data concerning the comparability of different tools are informative for estimating the risk of CVD, but accuracy of the outcome predictions should also be considered. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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