| Autor: |
Scheibe E, Streubel U, Braun V |
| Jazyk: |
němčina |
| Zdroj: |
Biomedica biochimica acta [Biomed Biochim Acta] 1985; Vol. 44 (9), pp. 1389-95. |
| Abstrakt: |
Hydrophilic areas of human polypeptide chains are obvious antigenic determinants for the allotypes of the Km-and Gm-system if they are located within special exposed segments of the native molecule. Allotype associated exchanges of amino acids are observed likewise in fewer hydrophilic segments. Even in strongly hydrophilic areas of polypeptide chains, antigenic determinants, characteristic for known iso- and allotypes, have not so far been observed. The prediction of antigenic determinants, exclusively based on the hydrophily of segments of polypeptide chains seems to be doubtful. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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