[Correction of impairments in functions of anticoagulation and insular systems of an organism by the regulatory peptide Leu-Pro-Gly-Pro].

Autor: Miasoedov NF, Andreeva LA, Liapina LA, Shubina TA, Grigor'eva ME, Obergan TIu
Jazyk: ruština
Zdroj: Izvestiia Akademii nauk. Seriia biologicheskaia [Izv Akad Nauk Ser Biol] 2013 May-Jun (3), pp. 341-4.
Abstrakt: It has been established that fivefold intranasal administration of the peptide Leu-Pro-Gly-Pro (1 mg/kg) to rats with developing refractory hyperglycemia leads to restoration and normalization of the functions of anticoagulation and insular systems. In the blood of experimental animals, there was a decrease in the sugar level and platelet aggregation and an increase in anticoagulant and all kinds of fibrinolytic (total, enzymatic, non-enzymatic, Hageman-dependent) activity.
Databáze: MEDLINE