| Autor: |
Adebayo KO; Department of Psychiatry, Ladoke Akintola University Teaching Hospital, Osogbo, Nigeria., Ibrahim N, Mosanya T, Eegunranti B, Suleiman B, Ayankunle A |
| Jazyk: |
angličtina |
| Zdroj: |
Therapeutic advances in psychopharmacology [Ther Adv Psychopharmacol] 2013 Oct; Vol. 3 (5), pp. 275-7. |
| DOI: |
10.1177/2045125313481026 |
| Abstrakt: |
Clozapine is regarded as a second-line and in some cases last-line antipsychotic known for its common life-threatening side effects, such as agranulocytosis, constipation and cardiomyopathies, but rarely haematemesis. We report a case of severe haemetemesis in a chronic schizophrenic patient managed with clozapine. The patient was a 46-year-old male being managed for chronic schizophrenia with treatment resistance who developed sudden severe haematemesis following commencement of clozapine for 6 weeks. The patient had 1.1 l of blood transfusion. The relevant literature is reviewed. Clozapine can be associated with a life-threatening haematemesis. Psychiatrists and other medical specialists need to be alert to the fatality of clozapine-induced haematemesis in the treatment of psychiatric disorders. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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