Weight gain in the first two years of life, asthma and atopy: the SCAALA cohort study.

Autor:	Matos SM; 1Institute of Collective Health,Federal University of Bahia,Rua Basílio da Gama s/n°,Campus Universitário do Canela,5° andar,40110-040 Salvador,Bahia,Brazil., Jesus SR; 2Division of Epidemiology and Collective Health,Multidisciplinary Health Unit,Federal University of Bahia,Salvador,Bahia,Brazil., Saldiva SR; 3Institute of Health,São Paulo State Department of Health,São Paulo,São Paulo,Brazil., Prado MS; 1Institute of Collective Health,Federal University of Bahia,Rua Basílio da Gama s/n°,Campus Universitário do Canela,5° andar,40110-040 Salvador,Bahia,Brazil., D'Innocenzo S; 1Institute of Collective Health,Federal University of Bahia,Rua Basílio da Gama s/n°,Campus Universitário do Canela,5° andar,40110-040 Salvador,Bahia,Brazil., Assis AM; 4School of Nutrition,Federal University of Bahia,Salvador,Bahia,Brazil., Rodrigues LC; 5Department of Epidemiology and Population Health,London School of Hygiene and Tropical Medicine,London,UK., Alcantara-Neves NM; 6Health Sciences Institute,Federal University of Bahia,Salvador,Bahia,Brazil., Cruz AA; 7ProAR,School of Medicine,Federal University of Bahia,Salvador,Bahia,Brazil., Simões Sde M; 8Center for Biological and Health Sciences,Department of Medicine,Federal University of Sergipe,Aracaju,Sergipe,Brazil., Fiaccone RL; 9Statistics Department,Federal University of Bahia,Salvador,Bahia,Brazil., Barreto ML; 1Institute of Collective Health,Federal University of Bahia,Rua Basílio da Gama s/n°,Campus Universitário do Canela,5° andar,40110-040 Salvador,Bahia,Brazil.
Jazyk:	angličtina
Zdroj:	Public health nutrition [Public Health Nutr] 2014 Nov; Vol. 17 (11), pp. 2537-45. Date of Electronic Publication: 2013 Oct 28.
DOI:	10.1017/S1368980013002899
Abstrakt:	Objective: To evaluate the association between weight gain in the first two years of life and the occurrence of wheezing, asthma, serum IgE, skin reactivity and pulmonary function. Design: Cohort study. Setting: The metropolitan region of Salvador, Bahia, Brazil. Subjects: The association was studied between 1997 and 2005 in 669 children up to 11 years of age. Data were collected on asthma and risk factors, both current factors and those present in the first years of life. Weight gain was considered fast when the Z-score was >0·67. Poisson regression was used in the multivariate statistical analysis. Results: Wheezing was reported in 25·6 % of the children. Weight gain was considered fast (Z-score >0·67) in 29·6 % of the children and slow (Z-score <-0·67) in 13·9 %. Children in the slow weight gain group had 36 % fewer symptoms of asthma (prevalence ratio = 0·65; 95 % CI 0·42, 0·99). Conclusions: Slower weight gain in the early years of life may constitute a protective factor against symptoms of asthma. The relevance of this finding for public health is not yet certain, since it is known that children with slow and fast weight gain may be more likely to develop adverse health consequences related to both these situations.
Databáze:	MEDLINE
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