| Autor: |
Kosolapov VA; Department of Pharmacology, Volgograd State Medical Academy; Laboratory of Pharmacology of Antioxidant Substances, Institute of Pharmacology, Volgograd State Medical Academy; Institute of Physical and Organic Chemistry, Southern Federal University, Rostov-on-Don, Russia. vad-ak@mail.ru., Eltsova LV, Spasov AA, Anisimova VA |
| Jazyk: |
angličtina |
| Zdroj: |
Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2013 Aug; Vol. 155 (4), pp. 461-3. |
| DOI: |
10.1007/s10517-013-2178-1 |
| Abstrakt: |
We studied antioxidant activity of new derivative of pyrrolo[1,2-α]benzimidazole RU-792 and compared its effects on free radical processes with those of the reference antioxidant Trolox in four model free-radical systems. RU-792 had high antioxidant activity determined by its intrinsic antiradical properties. RU-792 was superior to Trolox by antioxidant activity in the models of Fe(2+)-induced chemiluminescence of lipids with 2,2-diphenyl-1-picrylhydrazyl and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid), but less effective in the model of luminol-dependent chemiluminescence. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
Full text from SpringerLink