Multiple sclerosis in South America: month of birth in different latitudes does not seem to interfere with the prevalence or progression of the disease.
| Autor: | Fragoso YD; Department of Neurology, Universidade Metropolitana de Santos, SantosSP, Brazil., Adoni T, Almeida SM, Alves-Leon SV, Arruda WO, Barbagelata-Aguero F, Brooks JB, Carra A, Claudino R, Comini-Frota ER, Correa EC, Damasceno A, Damasceno BP, Díaz EC, Elliff DG, Fiore AP, Franco CM, Giacomo MC, Gomes S, Gonçalves MV, Grzesiuk AK, Inojosa JL, Kaimen-Maciel DR, Lin K, Lopes J, Lourenço GA, Martínez AD, Melcon MO, Morales Nde M, Morales RR, Moreira M, Moreira SV, Oliveira CL, Oliveira FT, Ribeiro JB, Ribeiro SB, Rodríguez CC, Russo L, Safanelli J, Shearer KD, Siquineli F, Vizcarra-Escobar D |
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| Jazyk: | angličtina |
| Zdroj: | Arquivos de neuro-psiquiatria [Arq Neuropsiquiatr] 2013 Sep; Vol. 71 (9A), pp. 573-9. |
| DOI: | 10.1590/0004-282X20130098 |
| Abstrakt: | Objective: To assess whether the month of birth in different latitudes of South America might influence the presence or severity of multiple sclerosis (MS) later in life. Methods: Neurologists in four South American countries working at MS units collected data on their patients' month of birth, gender, age, and disease progression. Results: Analysis of data from 1207 MS patients and 1207 control subjects did not show any significant variation in the month of birth regarding the prevalence of MS in four latitude bands (0-10; 11-20; 21-30; and 31-40 degrees). There was no relationship between the month of birth and the severity of disease in each latitude band. Conclusion: The results from this study show that MS patients born to mothers who were pregnant at different Southern latitudes do not follow the seasonal pattern observed at high Northern latitudes. |
| Databáze: | MEDLINE |
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