| Autor: |
Martinez-Perdiguero J; CIC microGUNE, Arrasate-Mondragón 20500, Spain. jmartinez@cicmicrogune.es., Retolaza A, Otaduy D, Juarros A, Merino S |
| Jazyk: |
angličtina |
| Zdroj: |
Sensors (Basel, Switzerland) [Sensors (Basel)] 2013 Oct 16; Vol. 13 (10), pp. 13960-8. Date of Electronic Publication: 2013 Oct 16. |
| DOI: |
10.3390/s131013960 |
| Abstrakt: |
In this work we present a surface plasmon resonance sensor based on enhanced optical transmission through sub-wavelength nanohole arrays. This technique is extremely sensitive to changes in the refractive index of the surrounding medium which result in a modulation of the transmitted light. The periodic gold nanohole array sensors were fabricated by high-throughput thermal nanoimprint lithography. Square periodic arrays with sub-wavelength hole diameters were obtained and characterized. Using solutions with known refractive index, the array sensitivities were obtained. Finally, protein absorption was monitored in real-time demonstrating the label-free biosensing capabilities of the fabricated devices. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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