Catalytic, enantioselective 1,3-dipolar cycloadditions of nitrile imines with methyleneindolinones.

Autor: Gerten AL; Department of Chemistry, Iowa State University, Ames, Iowa 50011, USA. lstanley@iastate.edu., Slade MC, Pugh KM, Stanley LM
Jazyk: angličtina
Zdroj: Organic & biomolecular chemistry [Org Biomol Chem] 2013 Dec 07; Vol. 11 (45), pp. 7834-7. Date of Electronic Publication: 2013 Oct 17.
DOI: 10.1039/c3ob41815d
Abstrakt: Catalytic, enantioselective 1,3-dipolar cycloadditions of nitrile imines with methyleneindolinones are reported. The spiro[pyrazolin-3,3'-oxindole] products are formed in good yields (up to 98%) and high enantioselectivity (up to 99% ee).
Databáze: MEDLINE