| Autor: |
Salganik RI, Tomsons VP, Pyrinova GB, Korokhov NP, Kiseleva EV, Khristolyubova NB |
| Jazyk: |
angličtina |
| Zdroj: |
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 1985 Aug 30; Vol. 131 (1), pp. 492-9. |
| DOI: |
10.1016/0006-291x(85)91829-7 |
| Abstrakt: |
Reverse transcriptase activity was found in rat liver enclosed in virus-like particles. Through hybridization with DNA probes of A- and C-type retroviruses and with the help of electron microscopy the virus-like particles have been identified as endogenous retroviruses related to the mouse intracisternal A-particles. Blot hybridization revealed the provirus DNA in the rat genome. The enzyme was isolated from the virus-like particles, purified and characterized. The main properties of the enzyme resemble those of the mammalian retrovirus reverse transcriptase. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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