The rare case of Alternaria alternata cutaneous and pulmonary infection in a heart transplant recipient treated by azole antifungals.

Autor: Sečníková Z; Dermatovenereology Department, 2nd Medical Faculty, Charles University, Bulovka Hospital, Prague, Czech Republic., Jůzlová K, Vojáčková N, Kazakov DV, Hošková L, Fialová J, Džambová M, Hercogová J
Jazyk: angličtina
Zdroj: Dermatologic therapy [Dermatol Ther] 2014 May-Jun; Vol. 27 (3), pp. 140-3. Date of Electronic Publication: 2013 Sep 23.
DOI: 10.1111/dth.12096
Abstrakt: We report a case of Alternaria alternata cutaneous and pulmonary infection in a 62-year-old man after heart transplantation treated by azole antifungals. Alternaria spp. belong to a group of opportunistic dematiaceous fungi with worldwide distribution. The cutaneous form of the infection in human is very rare and occurs predominantly among immunosuppressed patients. Therefore, diagnosis is often delayed or not reached at all. Appropriate treatment is not standardized and remains a matter of discussion. According to current studies, the best results are obtained with systemic azole antifungal therapy combined with surgical intervention.
(© 2013 Wiley Periodicals, Inc.)
Databáze: MEDLINE
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