Prospective Urban Rural Epidemiology (PURE) study: Baseline characteristics of the household sample and comparative analyses with national data in 17 countries.

Autor: Corsi DJ; Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada; Harvard Center for Population and Development Studies, Cambridge, MA. Electronic address: djcorsi@hsph.harvard.edu., Subramanian SV, Chow CK, McKee M, Chifamba J, Dagenais G, Diaz R, Iqbal R, Kelishadi R, Kruger A, Lanas F, López-Jaramilo P, Mony P, Mohan V, Avezum A, Oguz A, Rahman MO, Rosengren A, Szuba A, Li W, Yusoff K, Yusufali A, Rangarajan S, Teo K, Yusuf S
Jazyk: angličtina
Zdroj: American heart journal [Am Heart J] 2013 Oct; Vol. 166 (4), pp. 636-646.e4. Date of Electronic Publication: 2013 Jul 27.
DOI: 10.1016/j.ahj.2013.04.019
Abstrakt: Background: The PURE study was established to investigate associations between social, behavioural, genetic, and environmental factors and cardiovascular diseases in 17 countries. In this analysis we compare the age, sex, urban/rural, mortality, and educational profiles of the PURE participants to national statistics.
Methods: PURE employed a community-based sampling and recruitment strategy where urban and rural communities were selected within countries. Within communities, representative samples of adults aged 35 to 70 years and their household members (n = 424,921) were invited for participation.
Results: The PURE household population compared to national statistics had more women (sex ratio 95.1 men per 100 women vs 100.3) and was older (33.1 years vs 27.3), although age had a positive linear relationship between the two data sources (Pearson's r = 0.92). PURE was 59.3% urban compared to an average of 63.1% in participating countries. The distribution of education was less than 7% different for each category, although PURE households typically had higher levels of education. For example, 37.8% of PURE household members had completed secondary education compared to 31.3% in the national data. Age-adjusted annual mortality rates showed positive correlation for men (r = 0.91) and women (r = 0.92) but were lower in PURE compared to national statistics (7.9 per 1000 vs 8.7 for men; 6.7 vs 8.1 for women).
Conclusions: These findings indicate that modest differences exist between the PURE household population and national data for the indicators studied. These differences, however, are unlikely to have much influence on exposure-disease associations derived in PURE. Further, incidence estimates from PURE, stratified according to sex and/or urban/rural location will enable valid comparisons of the relative rates of various cardiovascular outcomes across countries.
(Copyright © 2013 Mosby, Inc. All rights reserved.)
Databáze: MEDLINE
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