Preterm infant with a late presentation of blueberry muffin lesions secondary to recombinant erythropoietin.

Autor: Rajpara A; University of Kansas Medical Center. jblackmon@kumc.edu., Blackmon J, Laarman R, Skaggs R, Liolios A, Lui D, Fraga G
Jazyk: angličtina
Zdroj: Dermatology online journal [Dermatol Online J] 2013 Sep 14; Vol. 19 (9), pp. 19618. Date of Electronic Publication: 2013 Sep 14.
Abstrakt: Our patient is a 26-week-old preterm female infant delivered by caesarean section secondary to severe maternal preeclampsia who had been receiving subcutaneous recombinant erythropoietin (r-EPO) for anemia of prematurity. At 8 weeks of age after 8 doses of r-EPO, the infant developed numerous non-blanching erythematous macules and patches located on the back, posterior shoulder, and posterior arms, concerning for late-onset blueberry muffin lesions. Biopsy of the lesions confirmed dermal hematopoiesis. After r-EPO was discontinued all skin lesions gradually resolved over a period of 2 weeks and never recurred.
Databáze: MEDLINE