Division of mitochondria in cultured human fibroblasts.

Autor: Fujioka H; Electron Microscopy Facility and Center for Mitochondrial Disease, School of Medicine, Case Western Reserve University, Cleveland, Ohio., Tandler B, Consolo MC, Karnik P
Jazyk: angličtina
Zdroj: Microscopy research and technique [Microsc Res Tech] 2013 Dec; Vol. 76 (12), pp. 1213-6. Date of Electronic Publication: 2013 Sep 05.
DOI: 10.1002/jemt.22287
Abstrakt: Ovate mitochondria in cultured human fibroblasts divide by pinching. In the process, as observed by transmission electron microscopy, a deep incisure of the surface membranes separates the organelle into two lobes connected by a slender isthmus. A single element of smooth endoplasmic reticulum (SER) invariably accompanies each incisure, extending deep into the cleft. When the ingrowing membranes meet and fuse with the antipodal membranes, fission occurs. Elongated mitochondria that give no indication of division often are cloaked by a single, continuous cistern of SER.
(Copyright © 2013 Wiley Periodicals, Inc.)
Databáze: MEDLINE
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