Hematological particularities and co-infections in injected drug users with AIDS.

Autor:	Brunetta DM; Center for Cell Based Therapy, Medical School of Ribeirão Preto, Universidade de São Paulo (USP), Ribeirão Preto, SP, Brazil. Electronic address: dbrunetta@hotmail.com., De Santis GC, Vilar FC, Brandão RA, Muniz RZ, Lima GM, Amorelli-Chacel ME, Covas DT, Machado AA
Jazyk:	angličtina
Zdroj:	The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases [Braz J Infect Dis] 2013 Nov-Dec; Vol. 17 (6), pp. 654-6. Date of Electronic Publication: 2013 Aug 31.
DOI:	10.1016/j.bjid.2013.03.010
Abstrakt:	HIV patients infected through injected drug use have poorer prognosis than other groups. We evaluated the hematological alterations and rates of co-infections in injected drug use patients with AIDS. Injected drug use patients were younger, predominantly of male gender, and presented lower CD4, total lymphocyte, and platelet counts, but not neutrophil count, than control group. Injected drug use patients had a higher rate of hepatitis C and mycobacteria infection. Furthermore, all injected drug use patients with hemoglobin <10.0 g dL(-1) and lymphocyte <1000μL(-1) had CD4 count lower than 100μL(-1). In conclusion, HIV-infected injected drug use patients constitute a special group of patients, and hemoglobin concentration and lymphocyte count can be used as surrogate markers for disease severity. (Copyright © 2012 Elsevier Editora Ltda. All rights reserved.)
Databáze:	MEDLINE
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